Trends and Issues in the Use of Garlic as A Natural Treatment for Lowering Blood Pressure in Hypertension Sufferers: Literature Review
DOI:
https://doi.org/10.22437/jkuj.v10i1.48108Keywords:
complementary therapy, garlic, Hypertension, treatment, trends and issuesAbstract
Introduction: Hypertension, or high blood pressure, is a global health problem whose prevalence continues to increase from year to year. The World Health Organization (WHO) reports that hypertension is one of the leading causes of death from cardiovascular disease worldwide. According to WHO data, approximately 1.28 billion adults aged 30–79 years suffer from hypertension globally. One natural ingredient that has attracted attention in the treatment of hypertension is garlic (Allium sativum). Thus, this paper aims to examine the effectiveness of garlic as a blood pressure-lowering drug in patients with hypertension and its underlying mechanism of action.
Methods: A comprehensive review of relevant studies was conducted, analyzing findings related to hypertension management, barriers to treatment, and the role of healthcare professionals and complementary therapies in improving patient compliance. This study used search engines and databases.
Result: The analyzed research findings consistently demonstrate that garlic has significant potential in lowering blood pressure among individuals with hypertension.
Conclusion: Garlic (Allium sativum Linn.) has proven to be significantly effective in reducing blood pressure among hypertensive patients in various preparations such as extracts, decoctions, and infusions, primarily through the action of allicin as a vasodilator, antioxidant, and anti-inflammatory agent.
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1. Amir, A., Rantesigi, N., & Agusrianto, A. (202?). Garlic infusion on lowering blood pressure in hypertensive patients: A literature review. Poltekita: Journal of Health Sciences, 16(1). https://doi.org/10.33860/jik.v16i1.685
2. Angraini, S. S., Nofia, V. R., Morika, H. D., & Sari, P. M. (2023). The effect of garlic consumption on blood pressure reduction in hypertensive patients. Jurnal Kesehatan, 15(2), 45–52.
3. Angraini, S. S., Nofia, V. R., Morika, H. D., & Sari, P. M. (2023). The effect of garlic consumption on reducing blood pressure in hypertensive patients in the neurology ward of RSUD Mayjen H.A. Thalib, Kerinci Regency. E-Jurnal Medika Udayana, 12(4), 7–12. https://doi.org/10.24843/MU.2023.V12.i04.P02
4. Cahyaningrum, I., & Cita, E. E. (2022). Blood pressure control with black garlic of single-clove garlic variant in hypertensive patients. Baiturrahim Jambi Academic Journal, 11(2). https://doi.org/10.36565/jab.v11i2.581
5. Chan, J., & Kim, J. H. (2023). Garlic and cardiovascular health: Evidence, controversies, and future perspectives. Nutrients, 15(6), 1425. https://doi.org/10.3390/nu15061425
6. Desreza, N., Erawati, & Masthura, S. (2023). The effect of garlic extract (Allium sativum Linn) on blood pressure reduction in elderly hypertensive patients at UPTD Puskesmas Peureulak, East Aceh. Jurnal Ilmu Kesehatan, 17(1), 33–40.
7. Dewi, R. T., Metasari, D., & Murwati. (2022). The effect of garlic drink on blood pressure reduction in hypertensive patients at Telaga Health Center, Bengkulu. Jurnal Penelitian Kesehatan, 10(1), 21–28.
8. Dima, L., Popescu, R., & Costache, R. (2022). Garlic supplementation and blood pressure control: An updated meta-analysis of randomized trials. Nutrients, 14(18), 3790. https://doi.org/10.3390/nu14183790
9. Efendi, P., Buston, E., Jumarta, H., & Buston, N. (2023). Garlic decoction and deep breathing relaxation therapy in reducing blood pressure among elderly with hypertension. Media Kesehatan Masyarakat Indonesia, 19(2), 112–120.
10. Haidar Alatas, H. A. (2023). Epidemiological study of the development of prehypertension into hypertension after 10 years. Herb-Medicine Journal: Periodical of Herbal, Medical, and Health Sciences.
11. Handayani, Y., Palamba, A., & Deva. (2022). The effect of garlic infusion on blood pressure in hypertensive patients in Lembang Kadundung, Tana Toraja. Jurnal Keperawatan Tropis, 8(3), 67–74.
12. Kadir, A. (2020). The relationship between the pathophysiology of hypertension and renal hypertension. Wijaya Kusuma Scientific Journal of Medicine, 5(1), 15–25.
13. Mahadewi, I. A. T., & Yowani, S. C. (2023). Bioactive allicin content activity in garlic (Allium sativum L.) as an antihypertensive. Proceedings of the National Workshop and Seminar on Pharmacy, 2, 62–67. https://doi.org/10.24843/WSNF.2022.v02.p62
14. Maki, K. C., Dicklin, M. R., & Rajaram, S. (2022). Dietary approaches for hypertension: Role of functional foods like garlic. Nutrients, 14(4), 789. https://doi.org/10.3390/nu14040789
15. Mangngi, A. P. (2022). The difference in effectiveness between garlic and celery consumption on blood pressure changes in menopausal women with hypertension in Sahraen Village, Kupang Regency. Scientific Journal of Medicine and Health, 1(3), 95–103. https://doi.org/10.55606/klinik.v1i3.752
16. Marhabatsar, N. S., & Sijid, S. A. (2024). Review: Hypertension in the cardiovascular system. Proceedings of the National Biology Seminar, 7(1). https://doi.org/10.24252/psb.v7i1.23080
17. Melinda, S., & Rosalina. (2022). The effect of garlic decoction (Allium sativum) on blood pressure in hypertensive patients. Jurnal Ilmiah Kesehatan, 14(2), 98–106.
18. Rahmadini, N. F., Safitri, N. A., Puspita, N. M. S., Amir, N. A. B., Atari, S. P., Paradhini, T. S., & Hunaifi, I. (2023). Literature study: Pathomechanism of cognitive disorders in hypertensive patients. Journal of Medicine and Health Sciences, 10(12). https://doi.org/10.33024/jikk.v10i12.12751
19. Ried, K., & Fakler, P. (2021). Potential of garlic (Allium sativum) in lowering blood pressure: Mechanisms, clinical evidence, and future directions. Current Hypertension Reports, 23(5), 12–19. https://doi.org/10.1007/s11906-021-01128-4
20. Silvia, N., & Chotimah, S. N. (2022). Mapping of primary hypertension patients in 2020–2021. Jakiyah: Scientific Journal of Public and Aisyiyah Health, 7(2). https://doi.org/10.35721/jakiyah.v7i2.146
21. Suhendro, P. (2024). The effect of garlic and onion consumption on reducing blood pressure in hypertensive patients in the working area of Puskesmas Kowel. Journal of Health Science and Technology, 2(1). https://doi.org/10.52234/jstk.v2i1.98
22. Sun, Y., Zhou, D., Wang, X., & Chen, Y. (2021). Effect of garlic supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials. Phytotherapy Research, 35(3), 1239–1250. https://doi.org/10.1002/ptr.6891
23. Sunarno, R. D., & Syarif, A. (2023). The effect of garlic infusion on lowering blood pressure in hypertensive patients: A literature review. NURSING UPDATE: Scientific Journal of Nursing Science, 14(3). https://doi.org/10.36089/nu.v14i3.1505
24. Susanti, U., & Kurniawati, R. (2020). The benefits of garlic for hypertension. Alkautsar Scientific Journal of Nursing and Health (JIKKA), 1(1). http://jurnal.akperalkautsar.ac.id/index.php/JIKKA/article/view/10
25. Wang, H., Zhu, Y., & Liu, S. (2021). Effects of garlic on blood pressure and endothelial function in hypertensive patients: A randomized controlled clinical trial. Frontiers in Nutrition, 8, 654321. https://doi.org/10.3389/fnut.2021.654321
26. Xu, Y., Zhang, Y., & Li, J. (2022). Antihypertensive effects of garlic: Insights from clinical trials and molecular mechanisms. Frontiers in Pharmacology, 13, 845612. https://doi.org/10.3389/fphar.2022.845612
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Copyright (c) 2025 Putri Irwanti Sari, Hasny Dwi Junizar, Hamidah, Indah Awaliyah Siregar, Rts Netisa Martawinarti, Muthia Mutmainnah, Yusnilawati
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