Metabolite profile of 25% ethanol extract of Areca nut (Areca catechu) which has potential as an anti-inflammatory

Authors

  • Humaryanto Medical Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi
  • Fairuz Medical Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi
  • Fathnur Sani Kasmadi Pharmacy Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi
  • Hanina Medical Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi
  • Tengku Arief Buana Perkasa Department of Biochemistry and Medical Biology, Faculty of Medicine and Health Sciences, Universitas Jambi

DOI:

https://doi.org/10.22437/proca.v1i2.50267

Keywords:

Metabolites, Extract, Ethanol 25%, Areca catechu

Abstract

Background: The areca nut plant has been preclinically tested for its pharmacological effects. A 25% ethanol extract is one type of extract suspected to have pharmacological potential. Objective: The purpose of this research is to describe the results of secondary metabolite profiles using LC-MS, which hopefully can provide an overview for further development. Methods: Extraction using the maceration method, then phytochemical screening, and preparation with methanol and DCM, then injected as much as 5 µl into UPLC-QToF-MS/MS, then analyzed with Masslynx 4.1 and Chemspider software. Results: The results have shown that the extract contained 12 compounds, several of which have the potential to be anti-inflammatory. Conclusion: Literature studies have several compounds that have the potential to be anti-inflammatory.

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Author Biographies

Humaryanto, Medical Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi

Medical Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi

Fairuz, Medical Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi

Medical Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi

Fathnur Sani Kasmadi, Pharmacy Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi

Pharmacy Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi

Hanina, Medical Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi

Medical Study Program, Faculty of Medicine and Public Health Sciences, Universitas Jambi

Tengku Arief Buana Perkasa, Department of Biochemistry and Medical Biology, Faculty of Medicine and Health Sciences, Universitas Jambi

Department of Biochemistry and Medical Biology, Faculty of Medicine and Health Sciences, Universitas Jambi

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Published

26-11-2025

How to Cite

Humaryanto, Fairuz, Kasmadi, F. S., Hanina, & Perkasa, T. A. B. (2025). Metabolite profile of 25% ethanol extract of Areca nut (Areca catechu) which has potential as an anti-inflammatory. Proceedings Academic Universitas Jambi, 1(2), 443–451. https://doi.org/10.22437/proca.v1i2.50267

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RESEARCH DISSEMINATION