Antioxidant activity potential of 96% ethanol extract from jackfruit (Artocarpus integer) peel based on IC50 value
DOI:
https://doi.org/10.22437/proca.v1i2.50328Keywords:
Jackfruit Peel; 96% Ethanol; DPPH, Antioxidant; IC50; Artocarpus integerAbstract
Background: Jackfruit (Artocarpus integer) peel is an agricultural waste with potential as a source of bioactive compounds. Objective: This study aims to evaluate the potential antioxidant activity of cempedak fruit peel extract using a 96% ethanol solvent. The extract, tested as fraction F3P, is believed to contain phenolic and flavonoid compounds that act as free radical scavengers. Extraction was performed using the maceration method. Methods: Antioxidant activity was tested in vitro using the DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical scavenging method at various concentrations, ranging from 20 ppm to 100 ppm. Based on the percentage inhibition data obtained, the IC50 (Inhibitory Concentration 50%) value was calculated through logarithmic/linear regression analysis. Results: The calculation results show that the 96% ethanol extract of cempedak fruit peel (fraction F3P) has an IC50 value of 8.872 ppm. This IC50 value, which is below 50 ppm, indicates that the extract has very strong antioxidant activity. The active compounds within it can reduce 50% of DPPH free radicals at very low concentrations. Conclusion: This study concludes that the 96% ethanol extract of cempedak fruit peel is a highly potent and valuable source of natural antioxidants. Utilizing jackfruit peel waste can be a solution for developing functional food products or health supplements.
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