Characteristic of the neutrophil-to-lymphocyte ratio (NLR) in patients with chronic low back pain
DOI:
https://doi.org/10.22437/proca.v1i2.50525Keywords:
Neutrophil-to-Lymphocyte Ratio (NLR); Chronic Low Back Pain (LBP); Inflammatory responsesAbstract
Background: Chronic low back pain (LBP) constitutes a worldwide public health issue that substantially impacts a considerable segment of the adult demographic. The Neutrophil-to-Lymphocyte Ratio (NLR) is recognized as a significant inflammatory biomarker for multiple health conditions, including musculoskeletal disorders like low back pain (LBP). Objective: The assessment of NLR in patients with LBP has aimed to identify a potential biomarker for elucidating the mechanisms underlying inflammation and chronic pain. Methods: This research is a cross-sectional analytical study. All samples in this study underwent a complete blood cell count examination. The neutrophil-to-lymphocyte ratio is calculated by dividing the neutrophil count by the lymphocyte count in routine blood test results. Statistical tests were conducted using SPSS software. Results: This study involved 31 participants. The analysis of the NLR indicated that 77.4% of participants were categorized as moderate, whereas 22.6% were classified as high. Furthermore, 18 individuals (58.06%) reported experiencing moderate pain (NPRS 4-6), while 13 individuals (41.94%) indicated severe pain (NPRS 7-10). Conclusion: This study found 77.4% of subjects had moderate NLR. Despite moderate to severe pain, their systemic inflammatory response had not fully established, as shown by a lack of NLR increase.
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Copyright (c) 2025 Attiya Istarini, Lipinwati, Hanina, Budi Justitia, Fitriyanti
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